Controlling the quality of Hematology reagents

Hematology reagents are important for the performance of diagnostic tests; the quality of the reagents should be observed consistently to be sure of obtaining accurate results, such quality includes reactive stability and control to ensure values within allowable limits.

Water, pipettes, saline solutions, test tubes, reagents, counters and all other materials required for hematology testing must meet strict and periodic quality controls; performing these quality controls is an important part of providing safe and efficient clinical diagnosis.

There is a wide range of reagents that should be used with new hematology kits in a responsible manner

This includes hematology reagents such as diluents, skeletal fluids, buffers, should also be used for performing these tests, these reagents should be monitored each time they are used to ensure the quality of the results.

Likewise; there are two main directives for the quality control of the reagents: internal control and external control; the internal control is performed with profile controls of test procedures through the patient control template, in which specific information about the results obtained is recorded.

The external quality control of the reagents generates high precision and efficiency in the results of the investigations

On the other hand; external control is performed with external quality controls and sample reference, this is carried out, to guarantee the consistency of the results; this involves the calibration of the instruments with external samples and helps to evaluate the accuracy and precision of the results obtained with the equipment.

These samples have known content, so that the results obtained can be verified; in addition to internal and external quality controls there are other strategies to monitor the quality of hematology reagents.

Strategies that can be added in the evaluation of quality control for reagents

These include trend monitoring, which refers to in-depth analysis of data obtained during internal and external controls in relation to the results obtained; key performance indicators (KPIs) are used to evaluate test results.

These KPIs can be considered to detect and correct both benchmark recurrence problems and inconsistencies such as batch or equipment errors.

Specialists must be sure that reagents are free of contaminants to avoid false positives and erroneous results

Finally, an important way to control the quality of hematology reagents is to ensure that all relevant safety, technological and quality standards are met; this includes confirming that the reagents used include the necessary additives in the correct concentrations.

It is clear that quality control is a critical part of a successful hematology laboratory; while many tests can be performed to ensure quality results, it is important to spend time carefully monitoring reagent quality to ensure accurate results and patient safety.

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